ChemicalBook > Product Catalog >Organic Chemistry >Hydrocarbons and derivatives >Hydrocarbon sulfonate >Tosyl chloride

Tosyl chloride

Tosyl chloride Suppliers list
Company Name: Shouguang Nuomeng Chemical Co Ltd.
Tel: 536-5119508
Products Intro: Product Name:P-Toluene sulfonyl chloride
Purity:99.5% Package:1T;3200USD
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Products Intro: Product Name:p-Toluene sulphonyl chloride
Purity:98%(Min,GC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-66670886
Products Intro: Product Name:p-Toluenesulfonyl Chloride
Purity:99% Package:100g ,1KG ,5KG 25KG
Company Name: Shanghai Bojing Chemical Co.,Ltd.
Tel: +86-21-37122233 +86-13795318958
Products Intro: Product Name:Tosyl chloride
Purity:99% Package:1kg;25kg;200kg Cardboard barrels Remarks:white crystalline
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Products Intro: Product Name:Tosyl chloride
Purity:99% Package:25KG;5KG;1KG

Tosyl chloride manufacturers

  • Tosyl chloride
  • $0.00 / 25Kg/Drum
  • 2022-02-25
  • CAS:98-59-9
  • Min. Order: 1Kg/Bag
  • Purity: 99.5%
  • Supply Ability: 1000mt/year
  • Tosyl Chloride
  • $1.00 / 1KG
  • 2021-12-01
  • CAS:98-59-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 ton
  • Tosyl chloride
  • $150.00 / 1ASSAYS
  • 2021-10-29
  • CAS:98-59-9
  • Min. Order: 10g
  • Purity: more than 99.6%
  • Supply Ability: 500kg/month

Related articles

  • What is Tosyl chloride?
  • Toluenesulfonyl chloride is a white to gray powdered solid with a distinctive odor. Insoluble in water and denser than water. ....
  • Sep 17,2020
Tosyl chloride Basic information
Tosyl chloride Chemical Properties Usage Production method
Product Name:Tosyl chloride
Synonyms:4-Tosyl chloride;4-METHYLBENZENESULFONYL CHLORIDE;4-METHYLBENZENESULPHONYL CHLORIDE;4-TOLUENESULFONYL CHLORIDE;4-Toluolsulfonyl chloride;4-toluene sulfochloride;AKOS BBS-00004428;P-Touenesulfonyl choride
Product Categories:1;Benzene derivatives;FINE Chemical & INTERMEDIATES;Protection & Derivatization Reagents (for Synthesis);Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry;synthesis of medicines;sipingji
Mol File:98-59-9.mol
Tosyl chloride Structure
Tosyl chloride Chemical Properties
Melting point 65-69 °C(lit.)
Boiling point 134 °C10 mm Hg(lit.)
density 1,006 g/cm3
vapor pressure 1 mm Hg ( 88 °C)
RTECS DB8929000
Fp 128 °C
storage temp. Store below +30°C.
solubility methylene chloride: 0.2 g/mL, clear
form Crystalline Powder
color White
Water Solubility hydrolyses
Sensitive Moisture Sensitive
Merck 14,9534
BRN 607898
Stability:Stable. Substances to be avoided include strong bases and strong oxidizing agents and water. Moisture sensitive.
CAS DataBase Reference98-59-9(CAS DataBase Reference)
NIST Chemistry ReferenceBenzenesulfonyl chloride, 4-methyl-(98-59-9)
EPA Substance Registry Systemp-Toluenesulfonyl chloride (98-59-9)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-29-41-38
Safety Statements 26-36/37/39-45-27-39
RIDADR UN 3261 8/PG 2
WGK Germany 1
Hazard Note Corrosive
HazardClass 8
PackingGroup II
HS Code 29049020
Hazardous Substances Data98-59-9(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 4680 mg/kg
MSDS Information
4-Toluene sulfochloride English
ACROS English
SigmaAldrich English
ALFA English
Tosyl chloride Usage And Synthesis
Tosyl chlorideToluenesulfonyl chloride is an important intermediate dyes in organic synthesis and raw materials for pesticides, there are three kinds of isomers, namely o-toluenesulfonyl chloride, m-toluenesulfonyl chloride and p-toluenesulfonyl chloride. Relative molecular mass is 190.65. All three stimulate skin and mucous membranes, commonly used is adjacent toluenesulfonyl chloride and p-toluenesulfonyl chloride.
O-toluenesulfonyl chloride, also known as 2-methyl-benzenesulfonyl chloride, 2-toluene-sulfonyl chloride, is colorless oily liquid. The relative density is 1.3383. Melting point is 10.2 ℃. Boiling point is 154 ℃ (4.800 × 103Pa), 126 ℃ (1.333 × 103Pa). The refractive index is 1.5565. It is insoluble in water, soluble in ether, benzene and ethanol.
M-toluenesulfonyl chloride, also known as 3-methyl-benzenesulfonyl chloride, 3-toluenesulfonyl chloride, is colorless oily liquid. Melting point is 11.7 ℃. Boiling point is 146 ℃ (2.933 × 103Pa). It is insoluble in water, soluble in alcohol, ether and benzene.
P-toluenesulfonyl chloride is also known as 4-methyl-benzenesulfonyl chloride, 4-toluenesulfonyl chloride. Precipitation from ether or petroleum ether is triclinic white flaky crystal. The relative density is 1.26. Melting point is 11. 7 ℃. Boiling point is 164 ℃ (4.4 × 103Pa), 151.6 ℃ (2.666 × 103Pa), 145~146 ℃ (2.000 × 103Pa), 134.5 ℃ (1.333 × 103Pa). It is insoluble in water, soluble in alcohol, benzene and ether.
Toluenesulfonyl chloride is called "TsCl", with strong nucleophilicity and substitution reaction with nucleophilic reagent. For example, reaction with the alcohol into the ester:
ROH + TsCl-Py → ROTs + Py + HCl-, reaction with amine and hydrazine respectively to generate the sulfonamide and sulfonyl hydrazide:

The above information were edited and collated by Xiaonan of Chemicalbook.
Chemical PropertiesWhite flaky crystal. melting point is 71 ℃. Boiling point is 151.6 ℃ (1.67kPa), 145-146 ℃ (2.0kPa). Soluble in alcohol, ether and benzene, insoluble in water.
Usage1. The goods is an intermediate for disperse dyes, azoic dyes, acid dyes. Also used in the production of drugs homosulfanilamide.
2. Used for the analysis Reagents, but also for organic synthesis, dye preparation and molecule rearrangement in the hormone synthesis.
3. Used for organic synthesis, sulfa drugs and as pesticide intermediates.
Production methodToluene chlorosulfonation production into o-toluenesulfonyl chloride, at the same time p-toluenesulfonyl chloride is also generated. The filter cake was separated from the o-toluenesulfonyl chloride, refined to obtain p-toluenesulfonyl chloride.
Chemical PropertiesWhite to yellow solid
UsesIt can be used for organic synthesis, for example: dyes, saccharin,etc.
UsesTosyl chloride is mainly used in the preparation of chemical derivatives in the pharmaceutical, plastics and organic chemical industries.
Usesp-Toluenesulfonyl chloride is used as a precursor in the production of dyes and saccharin. It acts as a dehydrating agent in the conversion of urea to carbodiimide and converts alcohols into the corresponding toluenesulfonate esters. It is also employed as a flow-promoting agent for paints, an adhesive, nitrocellulose, coating material and as a plasticizer for polyamides. Furthermore, it serves as an antistatic agent, as a gloss enhancer in plastic film preparations and as a basic material of electroplating solutions.
General DescriptionA white to gray powdered solid with a distinctive odor. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.
Air & Water ReactionsInsoluble in water.
Health HazardTOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardNon-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Contact allergensTosyl chloride is used mainly in the preparation of chemical derivatives in the pharmaceutical, plastics, and organic chemical industries.
Purification MethodsMaterial that has been standing for a long time contains tosic acid and HCl and has m ca 65-68o. It is purified by dissolving (10g) in the minimum volume of CHCl3 (ca 25mL) filtered, and diluted with five volumes (i.e. 125mL) of pet ether (b 30-60o) to precipitate impurities. The solution is filtered, clarified with charcoal and concentrated to 40mL by evaporation. Further evaporation to a very small volume gives 7g of white crystals which are analytically pure, m 67.5-68.5o. (The insoluble material is largely tosic acid and has m 101-104o.) [Pelletier Chem Ind (London) 1034 1953.] It also crystallises from toluene/pet ether in the cold, from pet ether (b 40-60o) or *benzene. Its solution in diethyl ether has been washed with aqueous 10% NaOH until colourless, then dried (Na2SO4) and crystallised by cooling in powdered Dry-ice. It has also been purified by dissolving in *benzene, washing with aqueous 5% NaOH , then dried with K2CO3 or MgSO4, and distilled under reduced pressure and can be sublimed at high vacuum [Ebel Chem Ber 60 20861927]. [Beilstein 11 IV 375.]
Tag:Tosyl chloride(98-59-9) Related Product Information
p-Toluenesulfonamide N-Ethyl-p-toluenesulfonamide Tosyl azide Tosyl cyanide P-Toluenesulfonic anhydride p-Toluenesulfonyl Isocyanate Sulfuryl chloride Benzyl chloride Methylene Chloride 2-?[[(2-?ethylphenyl)?(2-?hydroxyethyl)?amino]?methyl]?-?3,?3-?difluoro-Propanenitrile Ammonium chloride Calcium chloride Toluene alpha-Toluenesulfonyl chloride METHYLSTYRENE Tosylmethyl isocyanide 4-Methylbenzenesulfonhydrazide 4-Nitrobenzenesulfonyl chloride