ChemicalBook >> CAS DataBase List >>1,1,3,3-Tetramethyldisiloxane


Chemical Name:
TMDSO;TETRAMETHYLDISILOXANE;TMDO;(Me2HSi)2O;Dimethylsilyl ether;Disiloxane, 1,1,3,3-tetramethyl-;5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine;CT2030;NSC 155369;SILOXANE HSI2
Molecular Formula:
Molecular Weight:
MOL File:
MSDS File:

1,1,3,3-Tetramethyldisiloxane Properties

Melting point <-78°C
Boiling point 70-71 °C (lit.)
Density 0.76 g/mL at 25 °C (lit.)
vapor pressure 250 hPa (20 °C)
refractive index n20/D 1.370(lit.)
Flash point 14 °F
storage temp. Store at <= 20°C.
form liquid
color colorless
Specific Gravity 0.757
explosive limit 0.8-62.9%(V)
Water Solubility DECOMPOSES
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 3: reacts with aqueous base
BRN 1733364
CAS DataBase Reference 3277-26-7(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference ((CH3)2SiH)2O(3277-26-7)
EPA Substance Registry System Disiloxane, 1,1,3,3-tetramethyl- (3277-26-7)


Risk and Safety Statements

Signal word  Danger
Hazard statements  H225
Precautionary statements  P210-P370+P378-P403+P235-P243-P403+P233
Hazard Codes  F
Risk Statements  11-36/37/38-16
Safety Statements  16-26-36-9-33-29
RIDADR  UN 2924 3/PG 2
WGK Germany  3
RTECS  JN1000000
Autoignition Temperature 240 °C
HazardClass  3
PackingGroup  II
HS Code  29310095

1,1,3,3-Tetramethyldisiloxane price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 235733 1,1,3,3-Tetramethyldisiloxane 97% 3277-26-7 25g $31.9 2022-05-15 Buy
Sigma-Aldrich 235733 1,1,3,3-Tetramethyldisiloxane 97% 3277-26-7 100g $105 2022-05-15 Buy
TCI Chemical T1437 1,1,3,3-Tetramethyldisiloxane >97.0%(GC) 3277-26-7 25mL $22 2022-04-27 Buy
TCI Chemical T1437 1,1,3,3-Tetramethyldisiloxane >97.0%(GC) 3277-26-7 250mL $125 2022-04-27 Buy
Alfa Aesar B23697 1,1,3,3-Tetramethyldisiloxane, 97% 3277-26-7 25g $37.6 2022-04-27 Buy
Product number Packaging Price Buy
235733 25g $31.9 Buy
235733 100g $105 Buy
T1437 25mL $22 Buy
T1437 250mL $125 Buy
B23697 25g $37.6 Buy

1,1,3,3-Tetramethyldisiloxane Chemical Properties,Uses,Production


1,1,3,3-Tetramethyldisiloxane is soluble in many organic solvents, such as aromatic hydrocarbon and petroleum hydrocarbons, and so on. This product is a kind of widely used organic silicon intermediates, and usually be used as organic silicon blocking agent. Due to containing reactive Si-H groups in the molecular structure, it can be used in the synthesis of copolymer macromolecule by hydrosilylation. The synthesis of copolymer macromolecule can be made into a series of reactive silicone oil.

Chemical Properties

Colorless or yellowish transparent liquid


1,1,3,3-Tetramethyldisiloxane is used as a monomer in the production of silicone polymers or silicone resins. It is used as a precursor to prepare other organosilicon compounds. It is also utilized in non-aqueous polymer preparation as well as a laboratory reagent.


1. Synthesis of polysiloxane containing faculties end groups.
2. Can be used for the preparation of high performance organic silicone surfactants.
3. Applicable to the production of many products, such as addition silicon rubber, silica gel, Hydrogenpolysiloxane and plastic, resin modifier, dendrite polymer special additives, etc.


1, 1, 3, 3-Tetramethyldisiloxane is a kind of siloxane derivative, and can be used as a monomer for the preparation of silicone polymers or silicone resins. It is used as an intermediate for preparing other organosilicon compounds. It is also used in non-aqueous polymer preparation as well as a laboratory reagent. In organic synthesis, it finds an application as an effective reducing agent in platinum-catalyzed reduction of carboxamides to amines as well as in the Au/TiO2-catalyzed hydrosilylation of carbonyl compounds (e.g., reduction of aldehydes or ketones) relative to monohydrosilanes. It can also enable a direct bromination of carboxylic acids in the presence of indium bromide (InBr3) as catalyst.

Purification Methods

1,Possible impurity is 1,1,5,5-tetramethyl-3-trimethylsiloxytrisiloxane b 154-155o/733mm. Fractionate it, collect fractions boiling below 80o and re-fractionate it. Its purity can be analysed by alkaline hydrolysis and measuring the volume of H2 liberated followed by gravimetric estimation of silica in the hydrolysate. It is unchanged when stored in glass containers in the absence of moisture for 2-3 weeks. Small amounts of H2 are liberated on long storage. Care should be taken when opening a container due to pressure developed. [Speier et al. J Am Chem Soc 79 974 1958, Emeléus & Smythe J Chem Soc 609 1958, IR: Kriegsmann Z Anorg Chem 299 78 1959, Beilstein 4 IV 3991.]


1,1,3,3-Tetramethyldisiloxane Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 325)Suppliers
Supplier Tel Email Country ProdList Advantage
Kingfirst chemical (nanjing) co.,ltd
86-25-84522992 CHINA 95 58
Hubei Co-Formula Material Tech Co., Ltd.
+86-27-84459282 CHINA 882 58
+86-13806087780 +86-13806087780 China 17384 58
CD Chemical Group Limited
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Henan Tianfu Chemical Co.,Ltd.
0371-55170693 China 22021 55

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View Lastest Price from 1,1,3,3-Tetramethyldisiloxane manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-05-17 1,1,3,3-Tetramethyldisiloxane
US $0.00-0.00 / KG 1KG 99 1 TON Jiangxi Huihe Chemical Co., Ltd.
2022-02-24 1,1,3,3-Tetramethyldisiloxane
US $10.00 / KG/Tin 1KG 99% 5000tons per month Wuhan Mulei New Material Technology Co. Ltd
2021-12-01 1, 1, 3, 3-Tetramethyldisiloxane
US $2.70 / Kg/Drum 10g 99% 10000kg Hebei Crovell Biotech Co Ltd
TETRAMETHYLDISILOXANE 1,3-Dihydrotetramethyldisiloxane Bis(dimethylsilyl) oxide bis(dimethylsilyl)oxide CT2030 Dimethylsilyl ether dimethylsilylether Disiloxane, 1,1,3,3-tetramethyl- sym-Tetramethyldisiloxane (CH3)2HSiOSiH(CH3)2 1,1,3,3-tetramethyl-disiloxan 1,1-Dihydro-1,1,3,3-tetramethyldisiloxane TMDO TMDSO 1,1,3,3-Tetramethyldisiloxane 3277-26-7 TMDSO TMDSO 1,1,3,3-Tetramethyldisiloxane [(dimethylsilyl)oxy]dimethylsilane SILOXANE HSI2 1,1,3,3-TETRAMETHYLDISILOXANE BIS(DIMETHYLSILYL) ETHER 1,1,3,3-TETRAMETHYLDISILOXANE,WACKER QUALITY Tetramethyldisiloxan 1,1,3,3,-TETRAMETHYLDISLOXANE 1,1,3,3-TETRAMETHYLDISILOXANE 97+% 1,1,3,3-Tetramethyl-1,3-dihydrodisiloxane 1,1,3,3-Tetramethyl-1,3-disiloxane 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine 1,1,3,3-Tetramethyl dihydro disiloxane 1,1,3,3-Tetramethyld (Me2HSi)2O 1,1,3,3-TetraMethyldisiloxane, 97% 100ML Dimethylsilyl ethe 1,1,3,3-TETRAMETHYLDISILOXANE FOR SYNTHE Tetramethyldiydrodisiloxane 1,1,3,3-Tetramethyldisiloxane, 99+% TMDSO (99.9999%-Si) PURATREM 1,1,3,3-Tetramethyldisiloxane, 98.5% (dimethyl-λ3-silanyl)oxy-dimethylsilicon (dimethyl-λ3-silanyl)oxy-dimethylsilicon 1,1,3,3-Tetramethyldisiloxane fandachem ETRAMETHYLDISILOXANE(CAS: 3277-26-7) NSC 155369 1,1,3,3-Tetramethyldisiloxane (TMDS) extrapure, 98% 3277-26-7 277-26-7 CH32SiH2O C4H14OSi2 Organometallic Reagents Organosilicon Si-H Compounds Si-O Compounds Si (Classes of Silicon Compounds) Reduction Siloxanes Tetramethyldisiloxane Silicone serier Reduction Si (Classes of Silicon Compounds) Si-H Compounds