ChemicalBook >> CAS DataBase List >>1,1'-Carbonyldiimidazole

1,1'-Carbonyldiimidazole

CAS No.
530-62-1
Chemical Name:
1,1'-Carbonyldiimidazole
Synonyms
CDI;CARBONYLDIIMIDAZOLE;DI(1H-IMIDAZOL-1-YL)METHANONE;N,N-CARBONYLDIIMIDAZOLE;Diimidazolyl ketone;1,1-CARBONYL DIIMIDAZOLE;CARBODIIMIDAZOLE;Di-imidazol-1-yl-methanone;1-(1H-imidazole-1-carbonyl)-1H-imidazole;carbonylimidazole
CBNumber:
CB0215374
Molecular Formula:
C7H6N4O
Molecular Weight:
162.15
MOL File:
530-62-1.mol
MSDS File:
SDS

1,1'-Carbonyldiimidazole Properties

Melting point 117-122 °C(lit.)
Boiling point 288.83°C (rough estimate)
Density 1.303 g/mL at 25 °C
refractive index n20/D1.434
storage temp. 2-8°C
solubility Soluble in dimethylformamide.
form Crystalline Powder
pka 2.90±0.10(Predicted)
color White to light cream
PH 7.7 (50g/l, H2O, 20℃)
PH Range 7.7 at 50 g/l
Water Solubility Insoluble in water
Sensitive Moisture Sensitive
Merck 14,1819
BRN 6826
Stability Stable, but moisture-sensitive. Incompatible with acids, strong oxidizing agents, water.
InChIKey PFKFTWBEEFSNDU-UHFFFAOYSA-N
CAS DataBase Reference 530-62-1(CAS DataBase Reference)
FDA UNII 63A10X1FSP
EPA Substance Registry System 1H-Imidazole, 1,1'-carbonylbis- (530-62-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314-H351-H318
Precautionary statements  P260-P264-P270-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P260h-P301+P330+P331-P303+P361+P353-P501a-P280-P305+P351+P338-P310
Hazard Codes  C,Xi,Xn
Risk Statements  22-34-36/37/38-40-36/38
Safety Statements  26-36/37/39-45-37/39-27-36/37
RIDADR  UN 3263 8/PG 2
WGK Germany  2
10-21
Hazard Note  Harmful/Corrosive/Moisture Sensitive
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29332990
Toxicity LD50 orally in Rabbit: 1071 mg/kg

1,1'-Carbonyldiimidazole price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 2G $27.6 2022-05-15 Buy
Sigma-Aldrich 8.51054 CDI 1,1′-Carbonyldiimidazole Novabiochem? 530-62-1 25g $151 2022-05-15 Buy
Sigma-Aldrich 8.51054 CDI 1,1′-Carbonyldiimidazole Novabiochem? 530-62-1 100g $451 2022-05-15 Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 5G $28.6 2022-05-15 Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 25G $104 2022-05-15 Buy
Product number Packaging Price Buy
8.02301 2G $27.6 Buy
8.51054 25g $151 Buy
8.51054 100g $451 Buy
8.02301 5G $28.6 Buy
8.02301 25G $104 Buy

1,1'-Carbonyldiimidazole Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

Used in the synthesis of peptides. Contains up to 10% imidazole.

Uses

peptide coupling reagent

Uses

CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.

Uses

1,1'-Carbonyldiimidazole is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.

Uses

Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.

General Description

1,1′-Carbonyldiimidazole (N,N′-carbonyldiimidazole) is a versatile peptide-forming reagent.

Purification Methods

Crystallise it from *benzene or tetrahydrofuran in a dry-box and store it dry. [Hearn Methods Enzymol 135 102 1987, Beilstein 23/4 V 245.]

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View Lastest Price from 1,1'-Carbonyldiimidazole manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-06-09 N,N-Carbonyldiimidazole
530-62-1
US $380.00 / kg 1kg 99% 500kg/month HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
2022-05-14 N,N-Carbonyldiimidazole
530-62-1
US $66.00 / kg 1kg 99% 20MT Hebei baicao biology science and technology co., ltd
2022-05-12 N,N-Carbonyldiimidazole
530-62-1
US $0.00 / g 10g 99.0% 10tons Wuhan Godbullraw Chemical Co.,ltd
CARBONYLDIIMIDAZOLE CARBODIIMIDAZOLE LABOTEST-BB LT00233203 IM2 C O DI(1H-IMIDAZOL-1-YL)METHANONE CDI (DIIMIDAZOL-1-YL)KETONE AKOS BBS-00004316 RARECHEM AK HZ 0060 1,1'-CARBONYLBIS-1H-IMIDAZOLE 1.1'-CARBONYL-BIS-IMIDAZOLE 1,1-CARBONYL DIIMIDAZOLE 1,1'-CARBONYLDIIMIDAZOLE 1H-IMIDAZOLE, 1,1'-CARBONYLBIS- N,N'-CARBONYLDIIMIDAZOLE N,N-CARBONYLDIIMIDAZOLE 1,1’-carbonylbis-1h-imidazol 1,1’-Carbonyldiimidazol 1,1'-Carbonylbis-1H-imidazole [Coupling Agent for Peptides Synthesis] 1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis] 1,1'-Carbonyldi(1H-imidazole) Bis(1H-imidazol-1-yl) ketone Bis(1-imidazolyl) ketone carbonyl-1,1’-bis-1H-diimidazole 1,1'-Carbonyldiimidazole,97% N,N'-Carbonyldiimidazole 1’-Carbonyldiimidazole 1,1'-Carbonyldiimida Di-imidazol-1-yl-methanone 1,1'-CarbonyldiiMidazole, >90% N'-CarbonyldiiMidazole (CDI) Product 2: N,N'-CarbonyldiiMidazole N,Nzzhlxy-Carbonyldiimidazole (CDI) CDI (Carbonyl Diimidazole) N,N-Carbonyldiimidazole Manufacturer 5% Pd-BaSO4 1,1'-CARBONYLDIIMIDAZOLE (CDI) CARBONYLDIIMIDAZOLE N,N carbonylimidazole CDI (N,N'-Carbonyldiimidazole) 1,1-Carbonyldiimidazole99% N,N'-Carbonyldiimidazole, 98%+ N,N'-Carbonyl diimidazole (CDI) N,N'-Carbonyldiimidazole,97% N,N'-CARBONYL-BIS-(IMIDAZOLE) N,NCARBONYLDIIMIDAZOLE,HIGHPURITY N,N'-Carbonyldiimidazole 98% 1,1''-CARBONYLDIIMIDZOLE CDI 1,1''-CARBONYLDIIMIDAZOLE N.N''-CARBONYL DICMIDAZOLE 1H-Imidazole,1,1-carbonylbis-(9CI) Bis(iMidazol-1-yl) Ketone Bis(iMidazol-1-yl)Methanone NSC 67203 1,1-CarbonyldiMidazole 1,1'-Carbonylbis-1H-imidazole CDI 1,1'-CarbonyldiiMdazole 1,1''-CARBONYLDIIMIDAZOLE FOR SYNTHESIS